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| Meryl Streep | Violet Weston | |
| Julia Roberts | Barbara Weston | |
| Chris Cooper | Charlie Aiken | |
| Ewan McGregor | Bill Fordham | |
| Margo Martindale | Mattie Fae Aiken | |
| Sam Shepard | Beverly Weston | |
| Dermot Mulroney | Steve Huberbrecht | |
| Julianne Nicholson | Ivy Weston | |
| Juliette Lewis | Karen Weston | |
| Abigail Breslin | Jean Fordham | |
| Benedict Cumberbatch | Little Charles Aiken | |
| Misty Upham | Johnna Monevata | |
| Will Coffey | Sheriff Deon Gilbeau | |
| Newell Alexander | Dr. Burke | |
| Jerry Stahl | Liquor Store Owner | |
| Meryl Streep | ||
| Julia Roberts | ||
| Chris Cooper | ||
| Ewan McGregor | ||
| Margo Martindale | ||
| Sam Shepard | ||
| Dermot Mulroney | ||
| Julianne Nicholson | ||
| Juliette Lewis | ||
| Abigail Breslin | ||
| Benedict Cumberbatch | ||
| Misty Upham | ||
| Will Coffey | ||
| Newell Alexander | ||
| Jerry Stahl |
| Director |
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| Producer |
George Clooney
Bob Weinstein |
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| Writer |
Akira Toriyama
Tracy Letts |
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| Cinematography |
Adriano Goldman
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A look at the lives of the strong-willed women of the Weston family, whose paths have diverged until a family crisis brings them back to the Midwest house they grew up in, and to the dysfunctional woman who raised them. |
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